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Created with Raphaël 2.1.0 07.07.2016 Opening of the national phase 17.10.2016 Preliminary and substantive examination 25.11.2016 Establishment of the national regular filing 31.01.2017 Publication of the PCT application (A2) 31.12.2019 Publication of the decision of grant (B1) 30.06.2020 Completion of the opposition filing period 31.01.2021 Issuance of patent (C1) 19.05.2024 22.12.2024 Valid until 22.12.2025 Payment of maintenance fee 22.12.2034 Patent expiration date

Patent in force


(11)Number of the document4666
(21)Number of the applicationa 2016 0078
(22)Filing date of the application2014.12.22
 Date of filing the request for examination (de fond) 07.09.2016
(71)Name(s) of applicant(s), code of the countryGILEAD SCIENCES INC., US;
(72)Name(s) of inventor(s), code of the countryBLOMGREN Peter A., US; CURRIE Kevin S., US; KROPF Jeffrey E., US; LEE Seung H., US; LO Jennifer R., US; MITCHELL Scott A., US; SCHMITT Aaron C., US; XIONG Jin-Ming, US; XU Jianjun, US; ZHAO Zhongdong, US; SWAMINATHAN Sundaramoorthi, US;
(73)Name(s) of owner(s), code of the countryGILEAD SCIENCES INC., US;
(54)Title of the inventionSyk inhibitors
(13)Kind-of-document code
C1, BOPI 01/2021
B1, BOPI 12/2019
A2, BOPI 01/2017
(51)International Patent Classification C07D 487/04 (2006.01); A61K 31/519 (2006.01); A61P 35/00 (2006.01); A61P 25/00 (2006.01);
(19)CountryUS
(41)Date of publication of the application2017.01.31
(45)Date of publication of patent granting decision:2019.12.31
(47)Date of issuance of patent2021.01.31
(30)Priority61/920,407, 2013.12.23, US
(74)Patent attorneyMARGINE Ion, Str. Lomonosov nr. 43, ap. 23, MD-2009, Chişinău, Republica Moldova
 Substantive examiner(s)JOVMIR Tudor, STAFI Radu, LEVIŢCHI Svetlana
(85)Date of introducing the national procedure2016.07.07
(86)International applicationPCT/US2014/071842, 2014.12.22
(87)International publicationWO 2015/100217 A1, 2015.07.02
 Payment for maintenance up to the date2024.12.22
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